THE IMPACT OF ALCOHOL USE DISORDER ON TUBERCULOSIS: A REVIEW OF THE EPIDEMIOLOGY AND POTENTIAL IMMUNOLOGIC MECHANISMS

The Impact of Alcohol Use Disorder on Tuberculosis: A Review of the Epidemiology and Potential Immunologic Mechanisms

Globally, an estimated 107 million people have an alcohol use disorder (AUD) leading to 2.8 million premature deaths each year.Tuberculosis (TB) is one of the leading causes of death globally and over 8% of global TB cases are estimated to be attributable to AUD.Social determinants of health such as poverty and undernutrition are often shared among

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Mycobacterium tuberculosis Cpn60.2 (GroEL2) blocks macrophage apoptosis via interaction with mitochondrial mortalin

Earlier studies suggested that Mycobacterium tuberculosis (Mtb) Allergy Relief proteins exported within the host macrophage play an essential role in tuberculosis pathogenesis.In fact, Mtb proteins interact with and deactivate key regulators of many macrophage functions such as phago-lysosome fusion and antigen presentation, resulting in the intrac

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Genome-Wide Identification and Expression Analysis of Heat Shock Transcription Factors in Camellia sinensis Under Abiotic Stress

The tea plant (Camellia sinensis) is an economically important crop that plays an important role not only in the beverage industry but also in the pharmaceutical industry.The environment has a great influence on the quality of the tea plant.Heat shock factors (Hsfs) are transcriptional regulators that control the plant response to adversity.However

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